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Take away your wrinkles,

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Have wrinkle free face.

Xeomin® (incobotulinumtoxinA), made by Merz Pharmaceuticals, is approved by the US FDA for the treatment of adults with cervical dystonia or blepharospasm and Moderate to severe frown lines between the eyebrows.  IncobotulinumtoxinA is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity.

FDA approval of XEOMIN®,  was based on the results of two U.S. clinical trials. A study cited in the Journal of Neurological Sciences on the efficacy and safety of XEOMIN® found it showed “non-inferiority” to Botox® when used in the same doses to treat cervical dystonia. It concluded that XEOMIN® is a safe and effective treatment for the disorder.

Xeomin® has now been approved for some cosmetic indications – Moderate to severe frown lines between the eyebrows. Similar to other drugs in this category, including Botox® and Dysport®, that also have FDA approval for the treatment of facial wrinkles. Now that Xeomin® is available and FDA approved, doctors can use it both on-label and off-label to treat the same facial lines treated by Botox® and Dysport®, including frown lines, crow’s feet and forehead wrinkles.

before after photo of botox xeomin and dysport


While it varies from patient to patient, generally, Botox takes seven to ten days until the effects of the treatment are seen.  Xeomin takes five to six days, while Dysport takes two to three days.

Since each person will react differently to each nueromodulator, over time, they will begin to favor which product works best for them.  When initially deciding on which neurotoxin to use, consult with a highly experienced provider that offers all three.  Additionally, Botox tends to be the most expensive option out of the three, but not necessarily produce the best results.


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